Fetal Plasma Prostaglandin F2.ALPHA. and Cortisol Responses to High-Dose Endotoxin Administration in Fetal Goats
نویسندگان
چکیده
منابع مشابه
Fetal plasma prostaglandin F(2alpha) and cortisol responses to high-dose endotoxin administration in fetal goats.
Intrauterine inflammation/infection has been associated with prenatal mortality and morbidity. However, few studies have been performed to investigate how the fetus responds to intrauterine inflammation/infection in utero. In the present study, fetal plasma prostaglandin (PG) F(2alpha) and cortisol responses to high-dose fetal endotoxin administration were evaluated in late gestation goats (n=8...
متن کاملFetal plasma testosterone correlates positively with cortisol.
BACKGROUND Fetal exposure to testosterone has been implicated in programming childhood behaviour, but little is known about the determinants of fetal testosterone concentrations. AIMS To investigate the relation between fetal testosterone and maternal and fetal cortisol. METHODS Clinically indicated blood samples taken from 44 human fetuses (mean gestational age 27 weeks, range 15-38), toge...
متن کاملFever and leukocytosis responses in goats to inhaled endotoxin are dose-dependent
Forty-five, weanling goats of mixed-sex, were randomly allotted to five treatment groups: no dust (n= 16), raw organic dust exposure for 15 min (n= 6), raw organic dust exposure for 1 h (n= 7), raw organic dust exposure for 3 h (n= 7), and raw organic dust exposure for 4 h (n= 9). Inhalation exposures were performed in a closed tent for the allotted times. The amount of endotoxin calculated to ...
متن کاملFetal Responses to Glucocorticoids
This chapter focuses primarily on the 30 years of often conflicting responses of intact fetuses to glucocorticoid exposure following Liggins' observation in 1969 that antenatal glucocorticoids induced early lung maturation in preterm sheep (1). Although the emphasis is on the surfactant system, other effects of glucocorticoid treatments on the fetal lung need to be discussed to dissociate them ...
متن کاملSubclinical exposure to low-dose endotoxin impairs EEG maturation in preterm fetal sheep.
Exposure to chorioamnionitis is strongly associated with neurodevelopmental disability after premature birth; however, it remains unclear whether subclinical infection affects functional EEG maturation. Chronically instrumented 103-104-day-old (0.7 gestational age: term 147 days) fetal sheep in utero were randomized to receive either gram-negative LPS by continuous low-dose infusion (100 ng iv ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Nippon Medical School
سال: 2003
ISSN: 1345-4676,1347-3409
DOI: 10.1272/jnms.70.151